The Olive Laboratory
Columbia University Medical Center
Our laboratory focuses on translational research and pancreatic cancer. We are working to facilitate the clinical realization of basic science principles in order to improve the care and treatment of pancreatic cancer patients. Our PI Kenneth Olive is an Assistant Professor at Columbia University and a member of the Herbert Irving Comprehensive Cancer Center. He has a primary appointment in the Division of Digestive and Liver Diseases in the Department of Medicine, and a secondary appointment in the Department of Pathology & Cell Biology.
Two postdoc positions open!
NEW - Position 1 - Cancer Metabolism
This scientist will lead a highly translational project on pancreatic cancer metabolism. The project developed from the high impact findings of our former graduate student, Mike Badgley, who identified the uptake of the amino acid cysteine/cystine as a key metabolic dependency of pancreatic cancer. Modulation of cysteine metabolism in mice with established pancreatic tumors led to the tumor-selective induction of ferroptosis, a non-cell autonomous cell death. We are now looking for a candidate with experience in cancer metabolism techniques to lead this project forward, with planned studies using in vivo carbon labeling as well as with a novel clinic-ready drug that targets this pathway. Full position description may be viewed HERE.
Position 2 - Cancer Immunotherapy
This scientist will lead the research component of an innovative new clinical trial in pancreatic cancer immunotherapy. This is a co-mentored position between Dr. Olive and Dr. Gulam Manji, an MD/PhD medical oncologist who leads the pancreatic cancer Phase 1 clinical trial effort at Columbia Presbyterian. Full position description may be viewed HERE.
For more information on positions in the Olive Lab, please email kenolive@columbia.edu.
This scientist will lead a highly translational project on pancreatic cancer metabolism. The project developed from the high impact findings of our former graduate student, Mike Badgley, who identified the uptake of the amino acid cysteine/cystine as a key metabolic dependency of pancreatic cancer. Modulation of cysteine metabolism in mice with established pancreatic tumors led to the tumor-selective induction of ferroptosis, a non-cell autonomous cell death. We are now looking for a candidate with experience in cancer metabolism techniques to lead this project forward, with planned studies using in vivo carbon labeling as well as with a novel clinic-ready drug that targets this pathway. Full position description may be viewed HERE.
Position 2 - Cancer Immunotherapy
This scientist will lead the research component of an innovative new clinical trial in pancreatic cancer immunotherapy. This is a co-mentored position between Dr. Olive and Dr. Gulam Manji, an MD/PhD medical oncologist who leads the pancreatic cancer Phase 1 clinical trial effort at Columbia Presbyterian. Full position description may be viewed HERE.
For more information on positions in the Olive Lab, please email kenolive@columbia.edu.
Our goals:
- make a meaningful, positive impact on the care of pancreatic cancer patients
- educate and train new scientists to tackle the cancer problem
- bridge the divide between medicine and science
- create a fun and productive environment where lab members can enjoy the processes of learning and discovery
Kenneth P. Olive, Ph.D. • 212-851-4678 • kenolive@columbia.edu
1130 Saint Nicholas Avenue, ICRC 217A, New York, NY 10032
1130 Saint Nicholas Avenue, ICRC 217A, New York, NY 10032