Computed Tomography (CT) is a widely used imaging modality in the clinical setting. A CT scan makes use of computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images of specific areas of a scanned object, allowing the user to see inside the object without cutting. Digital geometry processing is used to generate a three-dimensional image of the inside of the object from a large series of two-dimensional radiographic images taken around a single axis of rotation. Cross-sectional images are used for diagnostic and therapeutic purposes in various medical disciplines. Many different investigators in multiple disciplines can benefit from the use of CT images. The Columbia University Medical Center is proud to have the Perkin-Elmer Quantum FX micro CT imaging system for preclinical small animal imaging.